Rabbit Anti- SOX2 Polyclonal Antibody

Cat# FNab08125

Size : 100ug

Brand : FineTest

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Synonyms:Transcription factor SOX-2|SOX2 antibody
Catalogue No.:FNab08125Reactivity:Human, Mouse, Rat, Zebrafish
Host:RabbitTested Application:ELISA, IF, WB, IHC
Clonality:polyclonalIsotype:IgG
Size
100µg Inquiry
Dispatch Time: About 3 working days
Product Name
SOX2 antibody
Catalogue No.
FNab08125
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
SRY(sex determining region Y)-box 2
Alternative Names
Transcription factor SOX-2|SOX2 antibody
UniProt ID
P48431
Observed MW
34 kDa
Application
Tested Applications
ELISA, IF, WB, IHC
Recommended dilution
WB: 1:2000-1:20000; IHC: 1:50-1:200; IF: 1:50-1:500
Validated Images
U-251 cells were subjected to SDS PAGE followed by western blot with FNab08125(SOX2 antibody) at dilution of 1:5000
Immunohistochemistry of paraffin-embedded human lung cancer tissue using FNab08125(SOX2 Antibody) at dilution of 1:100
Immunofluorescent analysis of ( 4% PFA ) fixed mouse embryo tissue using FNab08125 ( SOX2 Antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Background
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206(By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal(By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation(By similarity).

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