rabbit Anti-COX 2 (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2) Polyclonal Antibody
Cat# C7904-82V-1Ea
Size : 1Ea
Brand : US Biological
Contact local distributor :
Phone : +1 850 650 7790
C7904-82V COX 2 (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2)
Clone Type
PolyclonalHost
rabbitSource
mouseSwiss Prot
Q05769Isotype
IgGGrade
Affinity PurifiedApplications
IC IF IHC WBCrossreactivity
Gp Hu Mk Mo Rt ShShipping Temp
Blue IceStorage Temp
-20°CCOX catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins: the conversion of arachidonic acid to prostaglandin H2. Recent discoveries of the induction of COX by a variety of stimuli such as phorbol esters, lipopolysaccharides, and cytokines led to the hypothosis that the inducible form of COX, COX-2, is responsible for the biosynthesis of prostaglandins under acute inflammatory conditions.1,2 COX-2 is a 72kD protein which has been cloned from a variety of species including human, mouse, rat, and sheep.
Applications:
Suitable for use in Immunohistochemistry, Western Blot and Immunofluorescence/Immunocytochemistry. Other applications not tested.
Recommended Dilution:
Immunohistochemistry: 1:300
Immunocytochemistry: 1:300
Western Blot: 1:200
Optimal dilution determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.