PRDX1 Antibody - N-terminal region
Cat# ARP48454_P050-25UL
Size : 25ul
Brand : Aviva Systems Biology
Contact local distributor :
Phone : +1 850 650 7790
PRDX1 Antibody - N-terminal region (ARP48454_P050)
| Datasheets/Manuals | Printable datasheet for anti-PRDX1 (ARP48454_P050) antibody |
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| Publications | A novel NRF2/ARE inhibitor gossypol induces cytotoxicity and sensitizes chemotherapy responses in chemo-refractory cancer cells Proteomic analysis of the hypothalamus of broiler-type Taiwan country chickens in response to acute heat stress Functional genomics study of acute heat stress response in the small yellow follicles of layer-type chickens |
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| Tested Species Reactivity | Human, Mouse |
| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | IHC, WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human PRDX1 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 92% |
| Peptide Sequence | Synthetic peptide located within the following region: SSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFV |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-PRDX1 (ARP48454_P050) antibody is Catalog # AAP48454 (Previous Catalog # AAPY01877) |
| Reference | Kim,J.H., (2008) Clin. Cancer Res. 14 (8), 2326-2333 |
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| Gene Symbol | PRDX1 |
| Gene Full Name | Peroxiredoxin 1 |
| Alias Symbols | PAG, PAGA, PAGB, PRX1, PRXI, MSP23, NKEFA, TDPX2, NKEF-A |
| NCBI Gene Id | 5052 |
| Protein Name | Peroxiredoxin-1 |
| Description of Target | PRDX1 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. It may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Three transcript variants encoding the same protein have been identified for this gene. |
| Uniprot ID | Q06830 |
| Protein Accession # | NP_002565 |
| Nucleotide Accession # | NM_002574 |
| Protein Size (# AA) | 199 |
| Molecular Weight | 22kDa |
| Protein Interactions | FUS; UBC; MDM2; RPA3; RPA2; RPA1; SUZ12; CACYBP; HECTD1; PRDX2; PRKDC; PPP2R5D; METTL1; PARK2; YWHAQ; VHL; EGFR; CDK2; RAD52; MPG; US3; SH2D1B; LUC7L; HCVgp1; PRDX4; IQCB1; BTRC; UBL4A; VCAM1; SMARCD1; FN1; DAB2; ADH5; ABL1; MYD88; MYC; ITGA4; TIPIN; EIF4 |
