PACS1 Antibody - C-terminal region - HRP

Cat# ARP64806_P050-HRP

Size : 100ul

Brand : Aviva Systems Biology

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Phone : +1 850 650 7790

PACS1 Antibody - C-terminal region : HRP (ARP64806_P050-HRP)

Datasheets/ManualsPrintable datasheet for anti-PACS1 (ARP64806_P050-HRP) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
ClonalityPolyclonal
HostRabbit
ConjugationHRP: Horseradish Peroxidase
ApplicationWB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: ALAIVGSPNSPYGDVIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFR
Concentration0.5 mg/ml
Blocking PeptideFor anti-PACS1 (ARP64806_P050-HRP) antibody is Catalog # AAP64806
Gene SymbolPACS1
Gene Full NamePhosphofurin acidic cluster sorting protein 1
Alias SymbolsSHMS, MRD17
NCBI Gene Id55690
Protein NamePhosphofurin acidic cluster sorting protein 1
Description of TargetThis gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.
Uniprot IDQ6VY07
Protein Accession #AAH55288
Nucleotide Accession #NM_018026
Protein Size (# AA)575
Molecular Weight62kDa
Protein InteractionsUBC; GGA3; CSNK2A1; FGFR1OP; PPP2CA; VAMP4; CLCN7; PPP2CB; PKD2; JUN; IGF2R; FURIN; TRPV4; nef;