OLIG2 Antibody

Cat# MBS850533-0,1mg

Size : 0,1mg

Brand : MyBiosource

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OLIG2 Antibody – Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS850533

This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal… More details

Product Overview

Online Datasheet in PDF
Product Name
OLIG2, Antibody
Full Product Name
OLIG2 Antibody
Product Gene Name
anti-OLIG2 antibody
Product Synonym Names
BHLHB1; OLIGO2; RACK17; PRKCBP2; bHLHe19; OLIG2
Isotype
IgG1
Clone Number
1G11
Host
Mouse
Species Reactivity
Human
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C.
Molecular Weight
32kDa
OMIM
606386
3D Structure
ModBase 3D Structure for Q13516
Immunogen
Purified recombinant fragment of human OLIG2 expressed in E. Coli.

Product Categories/Family for anti-OLIG2 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-OLIG2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-OLIG2 antibody
WB: 1:500-1:2000
IHC: 1:200-1:1000
IF: 1:200-1:1000
ELISA: 1:10000

Western Blot (WB) of anti-OLIG2 antibody

Figure 1: Western blot analysis using OLIG2 mAb against HEK293 (1) and OLIG2-hIgGFc transfected HEK293 (2) cell lysate.
Mouse Anti-OLIG2 Antibody – Cat# MBS850533

Immunohistochemistry (IHC) of anti-OLIG2 antibody

Figure 2: Immunohistochemical analysis of paraffin-embedded muscle tissues using OLIG2 mouse mAb with DAB staining.
Mouse Anti-OLIG2 Antibody, Immunohistochemistry (IHC) – Cat# MBS850533

Testing Data of anti-OLIG2 antibody

Mouse Anti-OLIG2 Antibody, Testing Data – Cat# MBS850533

Other Notes

Small volumes of anti-OLIG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OLIG2 purchase

MBS850533 is an antibody targeting OLIG2. Also known as OLIG2 Antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for OLIG2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
oligodendrocyte transcription factor 2
NCBI Official Synonym Full Names
oligodendrocyte transcription factor 2
NCBI Official Symbol
OLIG2
NCBI Official Synonym Symbols
BHLHB1; OLIGO2; RACK17; PRKCBP2; bHLHe19
UniProt Protein Name
Oligodendrocyte transcription factor 2
UniProt Synonym Protein Names
Class B basic helix-loop-helix protein 1; bHLHb1; Class E basic helix-loop-helix protein 19; bHLHe19; Protein kinase C-binding protein 2; Protein kinase C-binding protein RACK17
Protein Family
Oligodendrocyte transcription factor
UniProt Gene Name
OLIG2
UniProt Synonym Gene Names
BHLHB1; BHLHE19; PRKCBP2; RACK17; Oligo2; bHLHb1; bHLHe19
NCBI Protein Information
oligodendrocyte transcription factor 2

NCBI Summary for OLIG2

This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008]
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UniProt Comments for OLIG2

Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-OLIG2 antibody

 Reference Product  PubMed Publications
 GFAP antibody  >127 publications with OLIG2 and GFAP
 NKX2-2 antibody  >64 publications with OLIG2 and NKX2-2
 SOX10 antibody  >58 publications with OLIG2 and SOX10
 SHH antibody  >50 publications with OLIG2 and SHH
 BMP4 antibody  >8 publications with OLIG2 and BMP4
 GAD1 antibody  >2 publications with OLIG2 and GAD1
 IRX3 antibody  >2 publications with OLIG2 and IRX3
 AKT1 antibody  >1 publications with OLIG2 and AKT1
 JAG2 antibody  >1 publications with OLIG2 and JAG2

Pathways associated with anti-OLIG2 antibody

 Products by Pathway  Pathway Diagram
 Neural Crest Differentiation Pathway antibodies  Neural Crest Differentiation Pathway Diagram

Diseases associated with anti-OLIG2 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >274 publications with OLIG2 and Nervous System Diseases
 Brain Diseases Antibodies  >208 publications with OLIG2 and Brain Diseases
 Disease Models, Animal Antibodies  >76 publications with OLIG2 and Disease Models, Animal
 Spinal Cord Diseases Antibodies  >47 publications with OLIG2 and Spinal Cord Diseases
 Nerve Degeneration Antibodies  >11 publications with OLIG2 and Nerve Degeneration
 Inflammation Antibodies  >11 publications with OLIG2 and Inflammation
 Seizures Antibodies  >9 publications with OLIG2 and Seizures
 Eye Diseases Antibodies  >8 publications with OLIG2 and Eye Diseases
 Neurobehavioral Manifestations Antibodies  >8 publications with OLIG2 and Neurobehavioral Manifestations
 Necrosis Antibodies  >8 publications with OLIG2 and Necrosis

Organs/Tissues associated with anti-OLIG2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >481 publications with OLIG2 and Brain
 Kidney Antibodies  >3 publications with OLIG2 and Kidney
 Lung Antibodies  >3 publications with OLIG2 and Lung
 Pineal Gland Antibodies  >1 publications with OLIG2 and Pineal Gland
 Testis Antibodies  >1 publications with OLIG2 and Testis
 Uncharacterized Tissue Antibodies  >1 publications with OLIG2 and Uncharacterized Tissue

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