Mouse Vldlr activation kit by CRISPRa

Cat# GA204604

Size : 1kit

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Mouse Vldlr activation kit by CRISPRa

SKU
GA204604
Vldlr CRISPRa kit - CRISPR gene activation of mouse very low density lipoprotein receptor
2 Weeks*
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Vldlr
Locus ID 22359
Components

GA204604G1, Vldlr gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204604G2, Vldlr gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204604G3, Vldlr gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001161420, NM_001347441, NM_013703
UniProt ID P98156
Synonyms AA408956; AI451093; AW047288
Summary Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.[UniProtKB/Swiss-Prot Function]
SKU Description Size
KN518900 Vldlr - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit

Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.