ACC1 antibody

Cat# FNab10685

Size : 100ug

Brand : FineTest

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Phone : +1 850 650 7790

Synonyms:Acetyl-CoA carboxylase 1 (ACC1)|Acetyl-Coenzyme A carboxylase alpha (ACC-alpha)|ACACA|ACAC|ACC1|ACCA antibody
Catalogue No.:FNab10685Reactivity:Human, Mouse
Host:MouseTested Application:ELISA, WB, IHC
Clonality:monoclonalIsotype:IgG2a
Size
100µg Inquiry
Dispatch Time: About 3 working days
Product Name
ACC1 antibody
Catalogue No.
FNab10685
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG2a
Clone ID
9D2
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
acetyl-Coenzyme A carboxylase alpha
Alternative Names
Acetyl-CoA carboxylase 1 (ACC1)|Acetyl-Coenzyme A carboxylase alpha (ACC-alpha)|ACACA|ACAC|ACC1|ACCA antibody
UniProt ID
Q13085
Observed MW
270 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:2000-1:10000; IHC: 1:100-1:500
Validated Images
various lysates were subjected to SDS PAGE followed by western blot with FNab10685(ACC1 antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab10685(ACC1 antibody) at dilution of 1:200
Background
ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase(FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.

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