Size : 10ug
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Tag | C-Flag & Strep Tag |
| Predicted MW | 14.7 kDa |
| Concentration | Please refer to the Certificate of Analysis (COA) for the lot-specific concentration before lyophilization. |
| Buffer | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with pH lower than 6.5 in subsequent experiments. |
| Reconstitution Method | 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube. 2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000 3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL) 4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample. |
| Storage | Store at -20°C to -80°C for 12 months in lyophilized form. |
| Stability | After reconstitution, if not intended for use within a month, aliquot and store at -80°C . Avoid repeated freezing and thawing. |
| Shipping | Ambient |
| Reference Data | |
| UniProt ID | P15382 |
| Synonyms | ISK, JLNS, JLNS2, LQT2/5, LQT5, MinK |
| Summary | The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. provided by RefSeq, Jul 2008 |
| Protein Categories | Cardiovascular diseases, Membrane Proteins |
| Protein Families | Ion Channels: Other |
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