IKZF3 Antibody - middle region - HRP
Cat# ARP39702_P050-HRP
Size : 100ul
Brand : Aviva Systems Biology
Contact local distributor :
Phone : +1 850 650 7790
IKZF3 Antibody - middle region : HRP (ARP39702_P050-HRP)
| Datasheets/Manuals | Printable datasheet for anti-ZNF559 (ARP39702_P050-HRP) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of Human IKZF3 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92%; Yeast: 83% |
| Peptide Sequence | Synthetic peptide located within the following region: YACQRRDALTGHLRTHSVEKPYKCEFCGRSYKQRSSLEEHKERCRTFLQS |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-ZNF559 (ARP39702_P050-HRP) antibody is Catalog # AAP39702 |
| Gene Symbol | IKZF3 |
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| Gene Full Name | zinc finger protein 559 |
| Alias Symbols | AIO, AIOLOS, ZNFN1A3 |
| NCBI Gene Id | 22806 |
| Protein Name | Zinc finger protein 559 |
| Description of Target | IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described. |
| Uniprot ID | Q9UKT9-14 |
| Protein Size (# AA) | 263 |
| Molecular Weight | 28kDa |
| Protein Interactions | STAMBPL1; EXOSC5; LGALS14; CABP5; PCID2; RCOR3; TBC1D22B; FANCL; MAGOHB; C1orf109; OAZ3; SPG21; CHCHD2; OSGIN1; POLM; PPP1R16B; ABLIM3; IKZF3; NEK6; FARS2; MRPL28; KAT5; BCAS2; AKAP9; FAM115A; EMC2; POLR1C; STX11; STK16; RAD51D; PSMA1; PRKAB2; PRKAA1; PIN |
