Quimigen Portugal > Hspd1 antibody - C-terminal region
Hspd1 antibody - C-terminal region
Brand : Aviva Systems Biology
Hspd1 Antibody - C-terminal region (ARP61107_P050)
| Datasheets/Manuals | Printable datasheet for anti-Hspd1 (ARP61107_P050) antibody |
|---|
| Tested Species Reactivity | Human, Mouse, Rat |
|---|---|
| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%; Yeast: 93%; Zebrafish: 86% |
| Peptide Sequence | Synthetic peptide located within the following region: LDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNA |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-Hspd1 (ARP61107_P050) antibody is Catalog # AAP61107 |
| Gene Symbol | Hspd1 |
|---|---|
| Gene Full Name | Heat shock protein 1 (chaperonin) |
| Alias Symbols | Hsp60, Hspd1-30p |
| NCBI Gene Id | 63868 |
| Protein Name | 60 kDa heat shock protein, mitochondrial |
| Description of Target | Hspd1 is a stress-inducible molecular chaperone which participates in protein folding. |
| Uniprot ID | P63038 |
| Protein Accession # | NP_071565 |
| Nucleotide Accession # | NM_022229 |
| Protein Size (# AA) | 573 |
| Molecular Weight | 63kDa |
| Protein Interactions | Gja1; Trim63; Park7; Snca; Bcl2l1; Bax; |
Biological pathways
| Name | # of Products |
|---|---|
| Positive regulation of interferon-alpha production | 52 |
| Positive regulation of interferon-gamma production | 108 |
| Positive regulation of T cell activation | 121 |
| T cell activation | 158 |
Biological process
| Name | # of Products |
|---|---|
| Activation of cysteine-type endopeptidase activity involved in apoptotic process | 100 |
| Anti-apoptosis | 239 |
| B cell activation | 26 |
| B cell cytokine production | 2 |
| B cell proliferation | 22 |
| Chaperone mediated protein folding requiring cofactor | 12 |
| De novo protein folding | 4 |
| Detection of misfolded protein | 1 |
| Isotype switching to IgG isotypes | 2 |
| MyD88-dependent toll-like receptor signaling pathway | 65 |
| Negative regulation of apoptotic process | 356 |
| Positive regulation of anti-apoptosis | 53 |
| Positive regulation of apoptotic process | 239 |
| Positive regulation of inflammatory response | 57 |
| Positive regulation of interferon-alpha production | 11 |
| Positive regulation of interferon-gamma production | 61 |
| Positive regulation of interleukin-10 production | 32 |
| Positive regulation of interleukin-12 production | 39 |
| Positive regulation of interleukin-6 production | 63 |
| Positive regulation of macrophage activation | 18 |
| Positive regulation of T cell activation | 28 |
| Positive regulation of T cell mediated immune response to tumor cell | 3 |
| Protein refolding | 11 |
| Protein stabilization | 64 |
| Response to ATP | 25 |
| Response to cocaine | 25 |
| Response to drug | 323 |
| Response to estrogen stimulus | 71 |
| Response to heat | 69 |
| Response to hydrogen peroxide | 47 |
| Response to hypoxia | 205 |
| Response to lipopolysaccharide | 175 |
| Response to organic cyclic compound | 128 |
| Response to organic substance | 64 |
| Response to unfolded protein | 47 |
| T cell activation | 68 |
Cellular components
| Name | # of Products |
|---|---|
| Cell surface | 369 |
| Coated pit | 38 |
| Coated vesicle | 2 |
| Cyclin-dependent protein kinase activating kinase holoenzyme complex | 6 |
| Cytoplasm | 4549 |
| Cytosol | 1868 |
| Early endosome | 107 |
| Extracellular space | 884 |
| Golgi apparatus | 794 |
| Intracellular membrane-bounded organelle | 233 |
| Lipopo | 1 |
Protein function
| Name | # of Products |
|---|---|
| ATP binding | 2814 |
| Cell surface binding | 163 |
| Chaperone binding | 213 |
| Insulin binding | 37 |
| Lipopolysaccharide binding | 102 |
| Misfolded protein binding | 28 |
| Nucleotide binding | 3928 |
| P53 binding | 139 |
| Protease binding | 376 |
| Protein binding | 12191 |
| Protein complex binding | 333 |
| Protein heterodimerization activity | 1132 |
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