Guinea Pig Polyclonal Anti-Vimentin
Cat# 03-GP53-25ul
Size : 25ul
Brand : American Research Products
Contact local distributor :
Phone : +1 850 650 7790
Anti-Vimentin Polyclonal Antibody
Category: Antibodies
Catalog
03-GP53
| Product Name | Anti-Vimentin Polyclonal Antibody |
|---|---|
| Description | This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract. |
| Synonyms | VIM, RP11-124N14.1, CTRCT30 |
| Clonality | Polyclonal |
| Immunogen | Vimentin purified from Calf lens |
| Specificity | Specific detection of vimentin (Mr 57,000 polypeptide). Tumors specifically detected: Sarcoma (including myosarcoma), lymphoma, melanoma. |
| Reactivity | Bovine, Human, Mouse |
| Applications | IHC, WB |
| Form | Stabilized Serum |
| Storage | 2-8C |
| References | Magin TM et al. (1990) Eur J Cell Biol 53: 333-348Boehnke K et al. (2007) Eur J Cell Biol 86: 731-746 |
| Background | This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract. |
| Supplier | ARP |
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