Glyco-Obeticholic acid [863239-60-5]

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Cat# NB-64-02714-2mg

Size : 2mg

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Brand : Neo Biotech

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Contact local distributor :

Phone : +1 850 650 7790

Glyco-Obeticholic acid

Catalog No. T11428 Copy Product Info

Purity: 99.95%

Glyco-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an agonist of the farnesoid X receptor (FXR).

Glyco-Obeticholic acid

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Glyco-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an agonist of the farnesoid X receptor (FXR).

Cas No. 863239-60-5

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Batch Information

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Purity:99.95%

Appearance:Solid

Color:White to Yellow

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COA HNMR HPLC

Product Introduction

Bioactivity

Description	Glyco-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an agonist of the farnesoid X receptor (FXR).
In vitro	In the liver, obeticholic acid undergoes conjugation with glycine to produce glyco-obeticholic acid, subsequently secreted into bile. Upon reaching the ileum and colon, microorganisms deconjugate this compound back into its original form, obeticholic acid, facilitating its reabsorption or fecal excretion.

Chemical Properties

Molecular Weight	477.68
Formula	C₂₈H₄₇NO₅
Cas No.	863239-60-5
Smiles	C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCC(NCC(O)=O)=O)C)(CC4)23)23)([C@H](O)[C@H](CC)[C@@]1(C[C@H](O)CC2)23)23)23
Relative Density.	1.125 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (104.67 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0935 mL	10.4673 mL	20.9345 mL	104.6726 mL
5 mM	0.4187 mL	2.0935 mL	4.1869 mL	20.9345 mL
10 mM	0.2093 mL	1.0467 mL	2.0935 mL	10.4673 mL
20 mM	0.1047 mL	0.5234 mL	1.0467 mL	5.2336 mL
50 mM	0.0419 mL	0.2093 mL	0.4187 mL	2.0935 mL
100 mM	0.0209 mL	0.1047 mL	0.2093 mL	1.0467 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.