Dehydroepiandrosterone sulfate [651-48-9]

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Cat# NB-64-15537-200mg

Size : 200mg

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Brand : Neo Biotech

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Phone : +1 850 650 7790

Dehydroepiandrosterone sulfate (Synonyms: Prasterone sulfate, PB-005, PB005, PB 005, DHEAS, DHEA sulfate)

Catalog No. T26366 Copy Product Info

Purity: 97.18%

Dehydroepiandrosterone sulfate (PB-005) influences the migration of neurons, arborization of dendrites, and formation of new synapses.

Dehydroepiandrosterone sulfate

Copy Product Info

Synonyms Prasterone sulfate, PB-005, PB005, PB 005, DHEAS, DHEA sulfate

Dehydroepiandrosterone sulfate (PB-005) influences the migration of neurons, arborization of dendrites, and formation of new synapses.

Cas No. 651-48-9

Batch Information

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Purity:97.18%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Dehydroepiandrosterone sulfate (PB-005) influences the migration of neurons, arborization of dendrites, and formation of new synapses.
In vitro	Dehydroepiandrosterone sulfate selectively increases the length of neurites containing the dendritic marker MAP-2 and increases neuronal excitability when directly applied to septal-preoptic neurons[1].
In vivo	Chronic administration of Dehydroepiandrosterone sulfate produces a dose-dependent effect on performance. In male Sprague-Dawley rats, Dehydroepiandrosterone sulfate (5-20 mg/kg; s.c.) is significantly effective in improving latency to reach the platform[3].
Synonyms	Prasterone sulfate, PB-005, PB005, PB 005, DHEAS, DHEA sulfate

Chemical Properties

Molecular Weight	368.49
Formula	C₁₉H₂₈O₅S
Cas No.	651-48-9
Smiles	03[C@@]12CCC(=O)[C@@]1(C)CC[C@@]1(03)[C@@]2(03)CC=C2C[C@H](CC[C@]12C)OS(O)(=O)=O
Relative Density.	1.1763 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 121.25 mg/mL (329.05 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (8.96 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7138 mL	13.5689 mL	27.1378 mL	135.6889 mL
5 mM	0.5428 mL	2.7138 mL	5.4276 mL	27.1378 mL
10 mM	0.2714 mL	1.3569 mL	2.7138 mL	13.5689 mL
20 mM	0.1357 mL	0.6784 mL	1.3569 mL	6.7844 mL
50 mM	0.0543 mL	0.2714 mL	0.5428 mL	2.7138 mL
100 mM	0.0271 mL	0.1357 mL	0.2714 mL	1.3569 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.