D-Galactose [59-23-4]
Cat# M9976-10g
Size : 10g
Brand : AbMole Bioscience
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D-(+)-Galactose
Quality Control & Documentation
Biological Activity
D-Galactose is a natural aldohexose and C-4 epimer of glucose, it accelerates the aging of invertebrates and mammals and is used as a model of aging. D-galactose given by oral route causes cognitive impairments in rats which are accompanied by oxidative damage. Cognitive impairments is observed in the open-field test in the 4th and 6th weeks after d-gal administration, as well as an impairment in spatial memory in the radial maze test after the 6th week of d-gal administration.
Chemical Information
| Molecular Weight | 180.16 |
| Formula | C6H12O6 |
| CAS Number | 59-23-4 |
| Solubility (25°C) | Water 100 mg/mL |
| Storage | RT, dry, sealed |
References
[1] Josiane Budni, et al. Behav Brain Res. Oral administration of d-galactose induces cognitive impairments and oxidative damage in rats
[2] Xu Cui, et al. J Neurosci Res. Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid