Images
Flow Cytometry
Application

Flow Cytometry

Flow cytometric analysis of human CRC CD3 T cells were treated with 4-1BB Humanized monoclonal antibody, clone D2D (Cat # RAB01123-M01J) to activated human CD3 T cells.

Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

4-1BB Humanized monoclonal antibody, clone D2D. Western Blot analysis of 4-1BB expression in Jurkat.

Protocol Download
QC Test

Western Blot detection against Immunogen.

  • Specifications

    Product Description

    Humanized recombinant monoclonal antibody raised against 4-1BB.Humanized Antibody,Humanized Antibodies,Humanized,Humanized Ab,Human Antibody,Human Ab,Hu Antibody,Human Antibodies,Human Abs,Hu Antibodies,HuAb,Recombinant Antibody,Recombinant Antibodies,Recombinant Monoclonal Antibody,RecomAb,Recombinant Ab,Recombinant Monoclonal Antibodies,Recombinant Abs,RAB,MAB,Recombinant Mab,CellTx,CellTherapy,Cell Therapy,MAB,monoclonal Ab,monoclonal antibody

    Antibody Species

    Human

    Immunogen

    Human 4-1BB recombinant protein

    Reactivity

    Human

    Form

    Liquid

    Purification

    Protein A sepharose

    Isotype

    Human IgG1

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Western Blot detection against Immunogen.

    Storage Buffer

    In PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Flow Cytometry

    Flow cytometric analysis of human CRC CD3 T cells were treated with 4-1BB Humanized monoclonal antibody, clone D2D (Cat # RAB01123-M01J) to activated human CD3 T cells.

    ELISA

    Western Blot (Cell lysate)

    4-1BB Humanized monoclonal antibody, clone D2D. Western Blot analysis of 4-1BB expression in Jurkat.
    Protocol Download

    Western Blot (Recombinant protein)

    Protocol Download
  • Gene Info — TNFRSF9

    Entrez GeneID

    3604

    Gene Name

    TNFRSF9

    Gene Alias

    4-1BB, CD137, CDw137, ILA, MGC2172

    Gene Description

    tumor necrosis factor receptor superfamily, member 9

    Omim ID

    602250

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq

    Other Designations

    4-1BB ligand receptor|CD137 antigen|OTTHUMP00000001360|OTTHUMP00000044294|T cell antigen ILA|homolog of mouse 4-1BB|induced by lymphocyte activation (ILA)|interleukin-activated receptor, homolog of mouse Ly63|receptor protein 4-1BB

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