TTL - human gene knockout kit via CRISPR, HDR mediated
Other products for "TTL or XM_086924"
Specifications
Product Data
Format
2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector
Luciferase-Puro
Target Symbol
TTL
Locus ID
150465
Components
KN207805G1, TTL gRNA vector 1 in pCas-Guide CRISPR vector
KN207805G2, TTL gRNA vector 2 in pCas-Guide CRISPR vector
KN207805LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer
These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 PubMed 14571137).supplied by OMIM, Mar 2008
TTL CRISPRa kit - CRISPR gene activation of human tubulin tyrosine ligase
1 kit
KN207805
TTL - human gene knockout kit via CRISPR, HDR mediated
1 kit
KN207805BN
TTL - human gene knockout kit via CRISPR, HDR mediated
1 kit
KN207805RB
TTL - human gene knockout kit via CRISPR, HDR mediated
1 kit
KN407805
TTL - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
1 kit
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
