Size : 500mg
Phone : +1 850 650 7790
Synonyms: Plantomycin, Phytomycin, Estreptomicina
| Description | Streptomycin sulfate (Phytomycin) is a sulfate salt of streptomycin that is a protein synthesis inhibitor. |
| In vitro | Strain RB1 exhibits an increased susceptibility to streptomycin that correlates positively with the concentration of CV in the growth medium. Furthermore, as the CV concentration rises, both cytochrome aa3 levels and the bacterium's sensitivity to streptomycin simultaneously escalate. It is noteworthy that cytochrome aa3 plays a critical role in the uptake of streptomycin by B. subtilis[1]. Additionally, streptomycin affects tRNA selection, with resistance mutations predominantly located in protein S12; these mutations are typically associated with enhanced specificity in the tRNA selection process[2]. |
| Synonyms | Plantomycin, Phytomycin, Estreptomicina |
| Molecular Weight | 1457.38 |
| Formula | C42H84N14O36S3 |
| Cas No. | 3810-74-0 |
| Smiles | N=C(N)N[C@@H]([C@@H]([C@H]([C@@H]([C@H]1O)O)NC(N)=N)O)[C@H]1O[C@H](O[C@H]([C@]2(O)C=O)C)[C@@H]2O[C@H]3[C@H]([C@@H]([C@H]([C@@H](O3)CO)O)O)NC.O=S(O)(O)=O.N=C(N)N[C@@H]([C@@H]([C@H]([C@@H]([C@H]4O)O)NC(N)=N)O)[C@H]4O[C@H](O[C@H]([C@]5(O)C=O)C)[C@@H]5O[C@H]6[C@H]([C@@H]([C@H]([C@@H](O6)CO)O)O)NC.O=S(O)(O)=O.O=S(O)(O)=O |
| Relative Density. | 1.2302 g/cm3 (Estimated) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 242.50 mg/mL (166.39 mM), Sonication is recommended.  DMSO: Insoluble | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
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