Western Blot (Tissue lysate)
The S1PR3 polyclonal antibody (Cat # PAB4720) is used in Western blot to detect S1PR3 in mouse kidney lysate.
- Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of S1PR3.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human S1PR3.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Tissue lysate)
The S1PR3 polyclonal antibody (Cat # PAB4720) is used in Western blot to detect S1PR3 in mouse kidney lysate. - Gene Info — S1PR3
Entrez GeneID
1903Protein Accession#
Q99500Gene Name
S1PR3
Gene Alias
EDG-3, EDG3, FLJ37523, FLJ93220, LPB3, MGC71696, S1P3
Gene Description
sphingosine-1-phosphate receptor 3
Omim ID
601965Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. [provided by RefSeq
Other Designations
G protein-coupled receptor, endothelial differentiation gene-3|OTTHUMP00000021612|S1P receptor EDG3|endothelial differentiation, sphingolipid G-protein-coupled receptor, 3|sphingosine 1-phosphate receptor 3
- Interactomes
- Pathways
- Diseases
- Publication Reference
- Induction of pro-angiogenic signaling by a synthetic peptide derived from the second intracellular loop of S1P3 (EDG3).
Licht T, Tsirulnikov L, Reuveni H, Yarnitzky T, Ben-Sasson SA.
Blood 2003 Sep; 102(6):2099.
Application：IF, WB, Human, HUVECs.
- Evidence for Edg-3 receptor-mediated activation of I(K.ACh) by sphingosine-1-phosphate in human atrial cardiomyocytes.
Himmel HM, Meyer Zu Heringdorf D, Graf E, Dobrev D, Kortner A, Schuler S, Jakobs KH, Ravens U.
Molecular Pharmacology 2000 Aug; 58(2):449.
- Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5.
An S, Zheng Y, Bleu T.
The Journal of Biological Chemistry 2000 Jan; 275(1):288.
- Induction of pro-angiogenic signaling by a synthetic peptide derived from the second intracellular loop of S1P3 (EDG3).