Recombinant Mouse GM-CSF Protein (CHO)

Biological Activity

Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory stimuli. Additionally, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) can stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma, and adenocarcinoma cell lines.

ED50 < 0.05 ng/ml, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of > 2.0 × 10⁷ units/mg.

Accession: # Q14AD9

Apparent Molecular Weight: 15~19 kDa, on SDS-PAGE under non-reducing conditions.

Lyophilized after extensive dialysis against PBS.

Product Citations

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  Cell Death Dis. 2023 Sep 21;14(9):619.

  Interfering with Rac1-activation during neonatal monocyte-macrophage differentiation influences the inflammatory responses of M1 macrophages
  Recombinant Mouse GM-CSF Protein (CHO) purchased from AbMole

Chemical Information

Solubility (25°C)	Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml.
Storage	Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.