Rabbit Anti-SHANK3 Polyclonal Antibody

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Phone : +1 850 650 7790

HPA003446

SH3 and multiple ankyrin repeat domains 3

Anti-SHANK3 Antibody

Polyclonal Antibody against HUMAN SHANK3

0.05 mg/ml

info@quimigen.pt

Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.

Target protein: SH3 and multiple ankyrin repeat domains 3
Target gene: SHANK3
Verified species reactivity: Human
Interspecies information: Highest antigen sequence indentity to the following orthologs: MOUSE - ENSMUSG00000022623 (95%)RAT - ENSRNOG00000052296 (94%)
Clonality: Polyclonal
Isotype: IgG
Host: Rabbit
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Material Safety Data Sheet
Purification method: Affinity purified using the PrEST antigen as affinity ligand
Antigen sequence: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
Notes: Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

Immunohistochemistry (IHC) recommended conditions
- Dilution: 1:50 - 1:200
- Retrieval method: HIER pH6

Shipping: Normally shipped at ambient temperatureStorage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Lilja J, Kaivola J, Conway JR, Vuorio J, Parkkola H, Roivas P, Dibus M, Chastney MR, Varila T, Jacquemet G, Peuhu E, Wang E, Pentikäinen U, Martinez D. Posada I, Hamidi H, Najumudeen AK, Sansom OJ, Barsukov IL, Abankwa D, Vattulainen I, Salmi M, Ivaska JNat Commun , 2024 Sep 12; 15:8002. Epub 2024 Sep 122024 Sep 12
Colombo E, Horta G, Roesler MK, Ihbe N, Chhabra S, Radyushkin K, Di Liberto G, Kreutzfeldt M, Schumann S, von Engelhardt J, Merkler D, Behl C, Mittmann T, Clement AM, Waisman A, Schmeisser MJProc Natl Acad Sci U S A , 2021 Nov 15; 118(47):e2110755118. Epub 2021 Nov 152021 Nov 15