PTGES3 (1A26) Monoclonal Antibody
Cat# bsm-54193R
Size : 100uL
Brand : Bioss
Contact local distributor :
Phone : +1 850 650 7790
Lane 1: Mouse Brain; Lane 2: SK-Br-3 Cells; Lane 3: Rat Lung; Probed with PTGES3 (1A26) Monoclonal Antibody (bsm-54193R) at 1:500 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.
IF(ICC) staining with PTGES3 (1A26) Monoclonal Antibody (bsm-54193R) at 1:100 in A431 cells (green). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100\/PBS.
IF(ICC) staining with PTGES3 (1A26) Monoclonal Antibody (bsm-54193R) at 1:100 in Hela cells (green). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100\/PBS.
Paraformaldehyde-fixed and paraffin-embedded Human Tonsil tissue incubated with PTGES3 (1A26) Monoclonal Antibody (bsm-54193R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
Paraformaldehyde-fixed and paraffin-embedded Human Colon Cancer tissue incubated with PTGES3 (1A26) Monoclonal Antibody (bsm-54193R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
Paraformaldehyde-fixed and paraffin-embedded Mouse Fallopian Tube tissue incubated with PTGES3 (1A26) Monoclonal Antibody (bsm-54193R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
Paraformaldehyde-fixed and paraffin-embedded Rat Testis tissue incubated with PTGES3 (1A26) Monoclonal Antibody (bsm-54193R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54193R |
| Product Name | PTGES3 (1A26) Monoclonal Antibody |
| Applications | WB, IHC-P, IF(ICC), IP, IHC |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Synthetic peptide within human p23 aa 50-100 |
| Clonality | Monoclonal |
| Clone # | 1A26 |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Target | |
| Gene ID | 10728 |
| Swiss Prot | Q15185 |
| Synonyms | Prostaglandin E synthase 3; Cytosolic prostaglandin E2 synthase; Hsp90 co-chaperone; Progesterone receptor complex p23; Telomerase-binding protein p23; cPGES; P23; TEBP. |
| Background | Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC-P | 1:200-400 |
| IF(ICC) | 1:50-200 |
| IP | 1-2ug |
| IHC | |