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Dispatch Time: About 3 working days
- Product Name
- PerCP-Cy5.5 Anti-Human CD123 Antibody(HI12H7)
- Catalogue No.
- PCP55-30052
- Form
- liquid
- Conjugation
- PerCP-Cy5.5
- Conjugation Information
- PerCP-Cy5.5 is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter).
- Clonality
- Monoclonal
- Isotype
- IgG1, κ
- Clone ID
- HI12H7
- Storage
- PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Alternative Names
- IL-3Rα|IL-6Receptoralpha antibody
- UniProt ID
- P26951
Application
- Tested Applications
- FC
- Recommended dilution
- Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Validated Images
Human peripheral blood mononuclear cells are stained with FITC Anti-Human CD45RO Antibody and PerCP-Cy5.5 Anti-Human CD123 Antibody(HI12H7) (Left). Mononuclear cells are stained with FITC Anti-Human CD45RO Antibody and PerCP-Cy5.5 Mouse IgG1, κ Isotype Control (Right). - Background
- CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.