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Dispatch Time: About 3 working days
- Product Name
- PE Anti-Mouse CD183/CXCR3 Antibody(CXCR3-173)
- Catalogue No.
- PE-30180
- Form
- liquid
- Conjugation
- PE
- Conjugation Information
- PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
- Clonality
- Monoclonal
- Isotype
- IgG
- Clone ID
- CXCR3-173
- Storage
- PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Alternative Names
- C-X-C chemokine receptor type 3|CD183/CXCR3|CXC-R3|CXCR-3|Cxcr3|IP-10 receptor|Interferon-inducible protein 10 receptor antibody
- UniProt ID
- O88410
Application
- Tested Applications
- FC
- Recommended dilution
- Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Validated Images
C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD3 Antibody and PE Anti-Mouse CD183/CXCR3 Antibody (Left). Splenocytes are stained with APC Anti-Mouse CD3 Antibody and PE Armenian Hamster IgG Isotype Control (Right). - Background
- CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.