PAX3 Antibody - middle region - HRP
Cat# ARP32446_T100-HRP
Size : 100ul
Brand : Aviva Systems Biology
Contact local distributor :
Phone : +1 850 650 7790
PAX3 Antibody - middle region : HRP (ARP32446_T100-HRP)
| Datasheets/Manuals | Printable datasheet for anti-PAX3 (ARP32446_T100-HRP) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human PAX3 |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Peptide Sequence | Synthetic peptide located within the following region: KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDL |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-PAX3 (ARP32446_T100-HRP) antibody is Catalog # AAP32446 (Previous Catalog # AAPP03442) |
| Reference | Wachtel,M., et al., (2004) Cancer Res. 64 (16), 5539-5545 |
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| Gene Symbol | PAX3 |
| Gene Full Name | Paired box 3 |
| Alias Symbols | WS1, WS3, CDHS, HUP2 |
| NCBI Gene Id | 5077 |
| Protein Name | Paired box protein Pax-3 |
| Description of Target | PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. |
| Uniprot ID | Q86UQ3 |
| Protein Accession # | NP_852126 |
| Nucleotide Accession # | NM_181461 |
| Protein Size (# AA) | 403 |
| Molecular Weight | 45kDa |
| Protein Interactions | PCTP; UBC; TAF1; POU3F2; HDAC1; TRIM28; HDAC10; SOX8; WWTR1; PAX3; DAXX; CIB1; SOX10; MEOX2; MEOX1; MITF; MSX1; Rad23b; PSMD4; TBP; IPO13; CNR1; |
