- Specifications
Product Description
Mouse monoclonal antibody raised against native NGFR.
Immunogen
Native from human WM245 melanoma cells.
Host
Mouse
Reactivity
Cat, Dog, Human, Pig, Rabbit, Sheep
Specificity
This antibody recognizes p75NTR (low affinity neurotrophin receptor).
Form
Lyophilized
Purification
Protein G purification
Isotype
IgG1
Recommend Usage
ELISA (1:5000)
Flow Cytometry (20 ug/mL)
Immunohistochemistry (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS, pH 7.2-7.6 (0.1% trehalose, without preservative).
Storage Instruction
Store at 4°C on dry atmosphere.
Reconstitute with the addition of 100 uL of sterile water. Centrifuge to remove any insoluble material. After reconstitution, keep aliquots and store at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability.
Aliquot to avoid repeated freezing and thawing. - Applications
Immunohistochemistry
Immunofluorescence
Flow Cytometry
- Gene Info — NGFR
Entrez GeneID
4804Protein Accession#
P08138Gene Name
NGFR
Gene Alias
CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR
Gene Description
nerve growth factor receptor (TNFR superfamily, member 16)
Omim ID
162010Gene Ontology
HyperlinkGene Summary
Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq
Other Designations
low affinity nerve growth factor receptor|low-affinity nerve growth factor receptor|nerve growth factor receptor
- Interactomes
- Pathways
- Diseases
- Publication Reference
- Inhibition within the nucleus tractus solitarius (NTS) ameliorates environmental exploration deficits due to cerebellum lesions in an animal model for autism.
Walker BR, Diefenbach KS, Parikh TN.
Behavioural Brain Research 2007 Jan; 176(1):109.
Application：IHC, Rat, Brain.
- Inhibition within the nucleus tractus solitarius (NTS) ameliorates environmental exploration deficits due to cerebellum lesions in an animal model for autism.
NGFR monoclonal antibody, clone ME20.4
Cat# MAB5596
Size : 100ug
Brand : Abnova
Contact local distributor :
Phone : +1 850 650 7790