| Size | |
|---|---|
| 100µg | Inquiry |
Dispatch Time: About 3 working days
- Product Name
- MAPK14 antibody
- Catalogue No.
- FNab06077
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 6D2
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- mitogen-activated protein kinase 14
- Alternative Names
- Mitogen-activated protein kinase 14 (MAP kinase 14 antibody, MAPK 14)|Cytokine suppressive anti-inflammatory drug-binding protein (CSAID-binding protein antibody, CSBP)|MAP kinase MXI2|MAX-interacting protein 2|Mitogen-activated protein kinase p38 alpha (MAP kinase p38 alpha)|Stress-activated protein kinase 2a (SAPK2a)|MAPK14|CSBP|CSBP1|CSBP2|CSPB1|MXI2|SAPK2A antibody
- UniProt ID
- Q16539
- Observed MW
- 38 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:1000-1:4000; IHC: 1:100-1:400
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06077(p38 MAPK Antibody) at dilution of 1:1000 
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab06077(p38 Antibody) at dilution of 1:200 - Background
- MAPK14 (mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.