Size : 100Tests
| Product Data | |
| Clone Name | RB6-8C5 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry: Use 10 µl of Neat-1/5 diluted antibody to label 10e6 cells in 100 µl. |
| Reactivity | Mouse |
| Antibody Host | Rat |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Normal murine bone marrow cells. |
| Specificity | This antibody recognises the mouse Gr-1 antigen. Clone RB6-8C5 reacts predominantly with the Ly-6G protein but weaker reactivity with the Ly-6C protein has been demonstrated. This Clone RB6-8C5 has been reported to deplete mouse mature neutrophils in vivo (3). We recommend the use of CL046LE for functional studies. |
| Buffer | PBS, pH 7.4 containing 0.09% Sodium Azide, 1% BSA and 5% Sucrose Label: PE State: Lyophilized purified Ig fraction Label: R. Phycoerythrin (RPE) |
| Reconstitution Method | Restore with 1 ml distilled water. |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | PE |
| Storage | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
| Stability | Shelf life: One year from despatch. |
| Shipping | Blue Ice |
| Gene Name | lymphocyte antigen 6 complex, locus G |
| Database Link | |
| Background | The Gr-1 antigen is primarily a marker of myeloid differentiation. In the bone marrow the level of Gr-1 expression is low on immature myeloblasts and increases as the myeloid cells mature to granulocytes. Gr-1 is also expressed on macrophages and transiently on differentiating monocytes. Expression of Gr-1 on a subpopulation of lymphocytes has also been reported. |
| Synonyms | Gr-1 Granulocyte marker |
| Reference Data | |
| Product Manuals |
| FAQs |
|
| SDS |
| Antibody Resources |
|