LMP1 Recombinant Protein

Cat# OPCA02861-100UG

Size : 100ug

Brand : Aviva Systems Biology

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Phone : +1 850 650 7790

Datasheets/ManualsPrintable datasheet for LMP1 Recombinant Protein (HHV-4) (OPCA02861)
Product Info
Predicted Species ReactivityEpstein-Barr virus|Epstein-Barr Virus
Product FormatLiquid or Lyophilized powder
Reconstitution and Storage-20°C or -80°C
Peptide SequenceYYHGQRHSDEHHHDDSLPHPQQATDDSSNQSDSNSNEGRHLLLVSGAGDGPPLCSQNLGAPGGGPNNGPQDPDNTDDNGPQDPDNTDDNGPHDPLPQDPDNTDDNGPQDPDNTDDNGPHDPLPHNPSDSAGNDGGPPQLTEEVENKGGDQGPPLMTDGGGGHSHDSGHDGIDPHLPTLLLGTSGSGGDDDDPHGPVQLSYYD
SourceYeast
Alias SymbolsProtein p63.
Protein NameLatent membrane protein 1
Description of TargetActs as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular proteins. For example, induces the sumoylation of host IRF7 thereby limiting its transcriptional activity and modulating the activation of innate immune responses.
Uniprot IDP13198
Protein Size (# AA)Cytoplasmic Domain
Molecular Weight23 kda