IRF5 Antibody - middle region - HRP
Cat# ARP31994_P050-HRP
Size : 100ul
Brand : Aviva Systems Biology
Contact local distributor :
Phone : +1 850 650 7790
IRF5 Antibody - middle region : HRP (ARP31994_P050-HRP)
| Datasheets/Manuals | Printable datasheet for anti-IRF5 (ARP31994_P050-HRP) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human IRF5 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85% |
| Peptide Sequence | Synthetic peptide located within the following region: IFFCFGEEWPDRKPREKKLITVQVVPVAARLLLEMFSGELSWSADSIRLQ |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-IRF5 (ARP31994_P050-HRP) antibody is Catalog # AAP31994 (Previous Catalog # AAPP02891) |
| Reference | Clark,H.F., (2008) Arthritis Rheum. 58 (5), 1264-1274 |
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| Gene Symbol | IRF5 |
| Gene Full Name | Interferon regulatory factor 5 |
| Alias Symbols | SLEB10 |
| NCBI Gene Id | 3663 |
| Protein Name | Interferon regulatory factor 5 |
| Description of Target | IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist. |
| Uniprot ID | Q13568 |
| Protein Accession # | NP_116032 |
| Nucleotide Accession # | NM_032643 |
| Protein Size (# AA) | 498 |
| Molecular Weight | 56kDa |
| Protein Interactions | SGTA; IRF5; COPS7B; COPS4; COPS5; COPS6; COPS8; COPS2; COPS3; UBC; GPS1; TRAF6; MYD88; RGS3; PPM1G; IRF6; HIVEP1; GRB2; CHUK; ALPI; MAVS; GTPBP2; CEP152; GTPBP1; SIN3A; NCOR2; NCOR1; KAT2B; HDAC1; EP300; CREBBP; TRIM15; IKBKE; TBK1; IRF3; XPO1; |
