IL1 beta (IL1B) Mouse Monoclonal Antibody [Clone ID: OTI3E1]

Cat# TA506443

Size : 100ul

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IL1 beta (IL1B) Mouse Monoclonal Antibody [Clone ID: OTI3E1]

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SKU
TA506443
IL1B mouse monoclonal antibody, clone OTI3E1 (formerly 3E1)
 
Specifications
Product Data
Clone Name OTI3E1
Application IF, IHC, WB
Recommended Dilution WB 1:1000~4000, IHC 1:150, IF 1:100
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human IL1B(NP_000567) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 30.6 kDa
Gene Name interleukin 1 beta
Database Link
Background The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. provided by RefSeq, Jul 2008
Synonyms IL-1; IL1-BETA; IL1F2
Reference Data
Protein Categories Allergies and autoimmune diseases, Chemokines, Cytokines, Growth Factors, Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Alzheimer's disease, Apoptosis, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Graft-versus-host disease, Hematopoietic cell lineage, MAPK signaling pathway, NOD-like receptor signaling pathway, Prion diseases, Toll-like receptor signaling pathway, Type I diabetes mellitus
SKU Description Size
CF506443 Carrier-free (BSA/glycerol-free) IL1B mouse monoclonal antibody, clone OTI3E1 (formerly 3E1) 100 ug
TA506443AM IL1B mouse monoclonal antibody,clone 3E1, Biotinylated 100 ul
TA506443BM IL1B mouse monoclonal antibody,clone 3E1, HRP conjugated 100 ul
TA506443S IL1B mouse monoclonal antibody, clone OTI3E1 (formerly 3E1) 30 ul

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