Human IL-4 ELISpot Set
Cat# EA101429
Size : 1x96wells(platenotincluded)
Product Data | |
Species | Human |
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Format | 1 x 96-well (plate not included) |
Assay Type | Enzyme-Linked ImmunoSpot (ELISpot) |
Assay Length | 3h after cell stimulation |
Signal | Colorimetric |
Specificity | Recognizes natural human IL-4 |
Cross Reactivity | No cross reactivity with other human cytokines |
Components | ELISpot Sets include capture and detection antibodies, Streptavidin - Alkaline Phosphatase conjugated, BSA, BCIP/NTB, blocking reagent. |
Background | The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
Gene Symbol | IL4 |
Locus ID | 3565 |
Shipping | Blue Ice |
Datasheet | |
SDS | |
Citations
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