HSPA8 Antibody - N-terminal region - HRP
Cat# ARP48445_P050-HRP
Size : 100ul
Brand : Aviva Systems Biology
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Phone : +1 850 650 7790
HSPA8 Antibody - N-terminal region : HRP (ARP48445_P050-HRP)
| Datasheets/Manuals | Printable datasheet for anti-HSPA8 (ARP48445_P050-HRP) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Goat, Pig, Sheep, Zebrafish |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | IHC, WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human HSPA8 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Goat: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100% |
| Peptide Sequence | Synthetic peptide located within the following region: MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERL |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-HSPA8 (ARP48445_P050-HRP) antibody is Catalog # AAP48445 (Previous Catalog # AAPY01867) |
| Sample Type Confirmation | HSPA8 is strongly supported by BioGPS gene expression data to be expressed in Jurkat, MCF7 |
| Reference | Luciano,M., (er) Eur. J. Hum. Genet. (2008) In press |
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| Gene Symbol | HSPA8 |
| Gene Full Name | Heat shock 70kDa protein 8 |
| Alias Symbols | LAP1, HSC54, HSC70, HSC71, HSP71, HSP73, LAP-1, NIP71, HEL-33, HSPA10, HEL-S-72p |
| NCBI Gene Id | 3312 |
| Protein Name | Heat shock cognate 71 kDa protein |
| Description of Target | HSPA8 belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA8 is a heat-shock cognate protein. The protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date.The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date. |
| Uniprot ID | P11142 |
| Protein Accession # | NP_006588 |
| Nucleotide Accession # | NM_006597 |
| Protein Size (# AA) | 646 |
| Molecular Weight | 71kDa |
| Protein Interactions | FUS; HSPBP1; TRIM38; STUB1; ISG15; UBC; TP53; BAG1; BAG3; IL32; NMI; AIRE; HAUS2; TUBGCP4; CEP250; TUBGCP2; TUBGCP3; TUBG1; AURKA; SUMO2; SUMO3; MDM2; LGALS3BP; CDKN1A; CDC20; HAUS1; STAU1; ST13; HSPA4; HSPA2; DNAJA1; GABRB1; EDRF1; DNAJC9; HSPA4L; HSPH1; |
