HMGCS2 antibody - N-terminal region

Cat# ARP41562_T100

Size : 100ul

Brand : Aviva Systems Biology

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HMGCS2 Antibody - N-terminal region (ARP41562_T100)

Datasheets/ManualsPrintable datasheet for anti-HMGCS2 (ARP41562_T100) antibody
Product Info
Publications

Possible role of intestinal fatty acid oxidation in the eating-inhibitory effect of the PPAR-α agonist Wy-14643 in high-fat diet fed rats

Authors: Karimian Azari, E., Leitner, C., et al.

Journal: PLoS One. 8, e74869 (2013)

Diacylglycerol acyltransferase-1 inhibition enhances intestinal fatty acid oxidation and reduces energy intake in rats

Authors: Schober, G., Arnold, M., et al.

Journal: J Lipid Res. 54, 1369-84 (2013)

Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human HMGCS2
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: PKDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQE
Concentration1.0 mg/ml
Blocking PeptideFor anti-HMGCS2 (ARP41562_T100) antibody is Catalog # AAP41562 (Previous Catalog # AAPP24247)
ReferenceBouchard,L., (2001) Pediatr. Res. 49 (3), 326-331
Gene SymbolHMGCS2
Gene Full Name3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
NCBI Gene Id3158
Protein NameHydroxymethylglutaryl-CoA synthase, mitochondrial
Description of TargetHMGCS2 condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Uniprot IDP54868
Protein Accession #NP_005509
Nucleotide Accession #NM_005518
Protein Size (# AA)508
Molecular Weight56kDa
Protein InteractionsUBC; APP; YWHAQ;