GLX351322 [835598-94-2]

Cat# NB-64-43784-10mg

Size : 10mg

Brand : Neo Biotech

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Phone : +1 850 650 7790

GLX351322

Catalog No. T8107 Copy Product Info
Purity: 99.93%
GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.

GLX351322

Copy Product Info

GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.

GLX351322
Cas No. 835598-94-2
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Purity:99.93%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
Targets&IC50
NOX2:40 μM, NOX4:5 μ M
In vitro
In long-term experiments (1-3 days), high-glucose-induced human islet cell reactive oxygen species (ROS) production and death were prevented by GLX351322.
Chemical Properties
Molecular Weight431.51
FormulaC21H25N3O5S
Cas No.835598-94-2
SmilesCCOC(=O)c1c(NC(=O)CN2CCN(CC2)C(=O)c2ccco2)sc2CCCc12
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 20 mg/mL (46.35 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (2.32 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3174 mL11.5872 mL23.1744 mL115.8722 mL
5 mM0.4635 mL2.3174 mL4.6349 mL23.1744 mL
10 mM0.2317 mL1.1587 mL2.3174 mL11.5872 mL
20 mM0.1159 mL0.5794 mL1.1587 mL5.7936 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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