FOS Antibody - C-terminal region - HRP
Cat# P100639_T100-HRP
Size : 100ul
Brand : Aviva Systems Biology
Contact local distributor :
Phone : +1 850 650 7790
FOS Antibody - C-terminal region : HRP (P100639_T100-HRP)
| Datasheets/Manuals | Printable datasheet for anti-FOS (P100639_T100-HRP) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Pig, Sheep |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the C terminal region of human FOS |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Sheep: 100% |
| Peptide Sequence | Synthetic peptide located within the following region: CTPSCTAYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLA |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-FOS (P100639_T100-HRP) antibody is Catalog # AAP30915 (Previous Catalog # AAPP01639) |
| Reference | Pan,X., et al., (2005) Biochem. Biophys. Res. Commun. 337 (4), 1052-1058 |
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| Gene Symbol | FOS |
| Gene Full Name | FBJ murine osteosarcoma viral oncogene homolog |
| Alias Symbols | p55, AP-1, C-FOS |
| NCBI Gene Id | 2353 |
| Protein Name | Proto-oncogene c-Fos |
| Description of Target | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. |
| Uniprot ID | P01100 |
| Protein Accession # | NP_005243 |
| Nucleotide Accession # | NM_005252 |
| Protein Size (# AA) | 380 |
| Molecular Weight | 41kDa |
| Protein Interactions | Psma4; CENPO; LMO3; ARFGAP1; USF2; USF1; PSMC5; PRKAA2; JUNB; JUN; GNG11; NQO1; ATF2; AQP1; LUZP4; CYTH4; CREB5; ABL1; CLU; ATP5I; APP; MTERF4; ANP32E; ARL6IP4; COPS4; CABP1; ZNF133; SET; NEFM; MAP1B; JUND; HSPA1A; MAF; FOS; DDIT3; CEBPG; CEBPE; CEBPA; AT |
