FA20A Antibody - N-terminal region
Cat# OAAB02382
Size : 400ul
Brand : Aviva Systems Biology
Contact local distributor :
Phone : +1 850 650 7790
FA20A Antibody - N-terminal region (OAAB02382)
| Datasheets/Manuals | Printable datasheet for FA20A Antibody - N-terminal region (OAAB02382) |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid. PBS with 0.09% (W/V) sodium azide. |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Host | Rabbit |
| Application | FC,IHC-P,WB |
| :: | Function: Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals. Cellular Location: Secreted. Golgi apparatus. Endoplasmic reticulum Tissue Location: Highly expressed in lung and liver. Intermediate levels in thymus and ovary. |
| Reconstitution and Storage | Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | This FA20A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human FA20A. |
| Purification | This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Concentration | Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Application Info | WB: 1:1000 IHC-P: 1:50~100 FC: 1:10~50 |
| Gene Symbol | FAM20A |
|---|---|
| Alias Symbols | AI1G, AIGFS, family with sequence similarity 20, member A, FP2747, protein FAM20A, pseudokinase FAM20A. |
| NCBI Gene Id | 54757 |
| Protein Name | Pseudokinase FAM20A|pseudokinase FAM20A isoform a precursor [Homo sapiens]|pseudokinase FAM20A isoform b [Homo sapiens] |
| Description of Target | Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals. |
| Uniprot ID | Q96MK3 |
| Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_001230675.1,NP_060035,NP_060035.2 |
| Molecular Weight | 61417 |
