ERCC8 Antibody - C-terminal region - HRP
Cat# ARP31542_P050-HRP
Size : 100ul
Brand : Aviva Systems Biology
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Phone : +1 850 650 7790
ERCC8 Antibody - C-terminal region : HRP (ARP31542_P050-HRP)
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| Datasheets/Manuals | Printable datasheet for anti-ERCC8 (ARP31542_P050-HRP) antibody |
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| Predicted Species Reactivity | Human, Rat, Dog, Horse, Pig, Rabbit |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | IHC, WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the C terminal region of human ERCC8 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Dog: 93%; Horse: 86%; Human: 100%; Pig: 79%; Rabbit: 79%; Rat: 79% |
| Peptide Sequence | Synthetic peptide located within the following region: QELYSGSRDCNILAWVPSLYEPVPDDDETTTKSQLNPAFEDAWSSSDEEG |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-ERCC8 (ARP31542_P050-HRP) antibody is Catalog # AAP31542 (Previous Catalog # AAPP02315) |
| Sample Type Confirmation | ERCC8 is supported by BioGPS gene expression data to be expressed in HepG2 |
| Reference | Groisman,R., et al., (2003) Cell113(3),357-367 |
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| Gene Symbol | ERCC8 |
| Gene Full Name | Excision repair cross-complementing rodent repair deficiency, complementation group 8 |
| Alias Symbols | CSA, CKN1, UVSS2 |
| NCBI Gene Id | 1161 |
| Protein Name | DNA excision repair protein ERCC-8 |
| Description of Target | ERCC8 (excision repair cross-complementing rodent repair deficiency, complementation group 8 isoform 1) is a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcript |
| Uniprot ID | Q13216 |
| Protein Accession # | NP_000073 |
| Nucleotide Accession # | NM_000082 |
| Protein Size (# AA) | 396 |
| Molecular Weight | 44kDa |
| Protein Interactions | CUL4A; CUL4B; DDB1; RUVBL2; ZNF24; PCNA; H1F0; ERCC6; UVSSA; DDA1; RFWD2; COPS4; COPS6; COPS3; TOP1; TP53; SSBP1; OGG1; MDM2; GTF2H2; CUL5; GPS1; DDB2; COPS2; COPS7A; COPS5; COPS8; RBX1; POLR2A; HMGN1; EP300; UBC; CSNK2B; XAB2; UQCRQ; CBR1; |
