• Specifications

    Product Description

    Rabbit recombinant monoclonal antibody raised against human Collagen VI.Recombinant Antibody,Recombinant Antibodies,Recombinant Monoclonal Antibody,RecomAb,Recombinant Ab,Recombinant Monoclonal Antibodies,Recombinant Abs,RAB,MAB,Recombinant Mab,MAB,monoclonal Ab,monoclonal antibody

    Antibody Species

    Rabbit

    Immunogen

    Original antibody is raised against ecombinant protein corresponding to human Collagen VI

    Theoretical MW (kDa)

    Calculated MW: 109 k

    Reactivity

    Human

    Form

    Liquid

    Preparation Method

    Mammalian cell (CHO) expression system

    Purification

    Affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunofluorescence (1:50-1:200)
    Immunohistochemistry (1:50-1/100)
    Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In 50 mM Tris-Glycine pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA).

    Storage Instruction

    Store at 4°C for short term. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemistry (Frozen sections)

    Immunocytochemistry

    Western Blot

  • Gene Info — COL6A1

    Entrez GeneID

    1291

    Protein Accession#

    P12109

    Gene Name

    COL6A1

    Gene Alias

    OPLL

    Gene Description

    collagen, type VI, alpha 1

    Omim ID

    120220 158810 254090 602475

    Gene Ontology

    Hyperlink

    Gene Summary

    The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq

    Other Designations

    alpha 1 (VI) chain (61 AA)|collagen VI, alpha-1 polypeptide

  • Interactomes
  • Pathways
  • Diseases
eProcurement