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Reagents and instruments for immunology, cell biology and molecular biology.

Citral [5392-40-5]

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Cat# NB-64-20117-100mg

Size : 100mg

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Phone : +1 850 650 7790

Brand : Neo Biotech

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Citral

(Synonyms: alpha-Citral) Copy Product Info

Synonyms: alpha-Citral

Catalog No. T3154 Copy Product Info

Citral A monoterpene, obtained from the essential oil of lemongrass, which has anti-pain and anti-inflammatory properties.

Cas No. 5392-40-5

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:83.55%

Appearance:Liquid

Color:Transparent

Product Introduction

Citral AI Summary

Citral exhibits cytotoxicity against human HeLa cells with an IC50 value of 39.65 μg/mL, suggesting its potential to inhibit cancer cell growth effectively. It achieves up to 60% growth inhibition at concentrations of 10 to 30 μg/mL over a 3-day period, indicating promising anti-cancer properties. Additionally, Citral demonstrates significant anti-inflammatory effects by inhibiting ear and paw edema in mouse models and shows analgesic properties by reducing thermal allodynia. However, higher doses of Citral have been associated with toxicity, evidenced by altered latency times and changes in food and water consumption in Swiss mice. This compound presents a compelling candidate for further research in cancer and inflammatory treatments, although its toxicity at elevated doses warrants careful consideration..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Citral A monoterpene, obtained from the essential oil of lemongrass, which has anti-pain and anti-inflammatory properties.
Synonyms	alpha-Citral

Chemical Properties

Molecular Weight	152.23
Formula	C₁₀H₁₆O
Cas No.	5392-40-5
Smiles	C\C(C)=C/CCC(C)=CC=O
Relative Density.	0.89. Temperature:20 °C.

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 240 mg/mL (1576.56 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (13.14 mM), Sonication is recommended.

10% DMSO+90% Saline: 10 mg/mL (65.69 mM), Suspension.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.5690 mL	32.8450 mL	65.6901 mL	328.4504 mL
5 mM	1.3138 mL	6.5690 mL	13.1380 mL	65.6901 mL
10 mM	0.6569 mL	3.2845 mL	6.5690 mL	32.8450 mL
20 mM	0.3285 mL	1.6423 mL	3.2845 mL	16.4225 mL
50 mM	0.1314 mL	0.6569 mL	1.3138 mL	6.5690 mL
100 mM	0.0657 mL	0.3285 mL	0.6569 mL	3.2845 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

α-CitralCitrala-Citral

Related Tags: Citral chemical structure | Citral formula | Citral molecular weight