TRITC-dextran (70 kDa)

Biological Activity

TRITC-dextran (70 kDa) is a fluorescent derivative of a dextran fraction with an average molecular weight of approximately 70000. TRITC dextrans are prepared from special dextran fractions by coupling to tetramethylrhodamine B isothiocyanate (mixed isomers). TRITC-dextrans are supplied as a pink powder which is readily soluble in water. TRITC-dextran is mainly used for studying permeability and microcirculation. It can also be used as a molecular size marker, for studies of drug delivery and more.

Chemical Information

Molecular Weight	70000
Solubility (25°C)	Soluble in water
Storage	4°C, dry, sealed

References

[1] Haoran Chen, et al. Front Chem. Mouse Strain- and Charge-Dependent Vessel Permeability of Nanoparticles at the Lower Size Limit

[2] Usmah Kawoos, et al. Front Neurol. N-acetylcysteine Amide Ameliorates Blast-Induced Changes in Blood-Brain Barrier Integrity in Rats

[3] Ngo Bich Nga Nathalie Tran, et al. Eur J Pharm Biopharm. Gradient-dependent release of the model drug TRITC-dextran from FITC-labeled BSA hydrogel nanocarriers in the hair follicles of porcine ear skin

[4] Alexa Patzelt, et al. J Control Release. Do nanoparticles have a future in dermal drug delivery?

[5] Rainelli Koumangoye, et al. Am J Physiol Cell Physiol. Loss of NKCC1 function increases epithelial tight junction permeability by upregulating claudin-2 expression