TCO-PEG3-Biotin

Referência NB-64-08763-1mg

Tamanho : 1mg

Marca : Neo Biotech

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TCO-PEG3-Biotin

Catalog No. T18766 Copy Product Info
TCO-PEG3-Biotin is a PEG-based cleavable ADC linker for synthesising antibody-drug conjugates (ADCs). Its TCO moiety undergoes click chemistry iEDDA reactions with molecules containing tetrazine groups.

TCO-PEG3-Biotin

Copy Product Info

TCO-PEG3-Biotin is a PEG-based cleavable ADC linker for synthesising antibody-drug conjugates (ADCs). Its TCO moiety undergoes click chemistry iEDDA reactions with molecules containing tetrazine groups.

TCO-PEG3-Biotin
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Product Introduction

Bioactivity
Description
TCO-PEG3-Biotin is a PEG-based cleavable ADC linker for synthesising antibody-drug conjugates (ADCs). Its TCO moiety undergoes click chemistry iEDDA reactions with molecules containing tetrazine groups.
In vitro
Antibody-drug conjugates (ADCs) consist of an antibody linked to a cytotoxin via an ADC linker[1].
Chemical Properties
Molecular Weight570.74
FormulaC27H46N4O7S
SmilesO=C(NCCOCCOCCOCCNC(CCCC[C@@H]1SC[C@H](N2)[C@@H]1NC2=O)=O)O[C@H]3CCC/C(07)=C/CC3
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (175.21 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7521 mL8.7606 mL17.5211 mL87.6056 mL
5 mM0.3504 mL1.7521 mL3.5042 mL17.5211 mL
10 mM0.1752 mL0.8761 mL1.7521 mL8.7606 mL
20 mM0.0876 mL0.4380 mL0.8761 mL4.3803 mL
50 mM0.0350 mL0.1752 mL0.3504 mL1.7521 mL
100 mM0.0175 mL0.0876 mL0.1752 mL0.8761 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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