SOX1 Antibody - middle region - HRP
Referência ARP31735_P050-HRP
Tamanho : 100ul
Marca : Aviva Systems Biology
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SOX1 Antibody - middle region : HRP (ARP31735_P050-HRP)
| Datasheets/Manuals | Printable datasheet for anti-SOX1 (ARP31735_P050-HRP) antibody |
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| Predicted Species Reactivity | Human, Mouse, Cow, Dog, Rabbit, Zebrafish |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human SOX1 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 93%; Dog: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Zebrafish: 80% |
| Peptide Sequence | Synthetic peptide located within the following region: AAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPPAPAHSRAPC |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-SOX1 (ARP31735_P050-HRP) antibody is Catalog # AAP31735 (Previous Catalog # AAPP02526) |
| Reference | Sabater,L., (2008) Neurology 70 (12), 924-928 |
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| Gene Symbol | SOX1 |
| Gene Full Name | SRY (sex determining region Y)-box 1 |
| Alias Symbols | - |
| NCBI Gene Id | 6656 |
| Protein Name | Transcription factor SOX-1 |
| Description of Target | SOX1 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. SOX1 may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. |
| Uniprot ID | O00570 |
| Protein Accession # | NP_005977 |
| Nucleotide Accession # | NM_005986 |
| Protein Size (# AA) | 391 |
| Molecular Weight | 39kDa |
| Protein Interactions | CTNNB1; |
