Sodium carbonate [497-19-8]

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Referência NB-64-11684-5g

Tamanho : 5g

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Marca : Neo Biotech

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Sodium carbonate (Synonyms: Soda Ash, Disodium carbonate, Carbonic acid disodium salt)

Catalog No. T22426 Copy Product Info

Sodium carbonate (Soda Ash) , is the disodium salt of carbonic acid with alkalinizing property.

Sodium carbonate

Copy Product Info

Synonyms Soda Ash, Disodium carbonate, Carbonic acid disodium salt

Sodium carbonate (Soda Ash) , is the disodium salt of carbonic acid with alkalinizing property.

Cas No. 497-19-8

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Appearance:solid

Color:White

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COA

Product Introduction

Sodium carbonate AI Summary

Sodium carbonate exhibits significant inhibitory activity against a broad spectrum of carbonic anhydrase (CA) enzymes from various species, including human CA isozymes and enzymes from pathogenic bacteria and fungi. Specifically, it shows moderate inhibition of human CA I and CA IV with Ki values of 15,000,000 nM and 5,700,000 nM, respectively, and weaker inhibition against human CA II and CA V with Ki values of 73,000,000 nM and 95,000,000 nM. It also inhibits recombinant beta-carbonic anhydrase from Streptococcus pneumoniae with a Ki value of 530,000 nM and alpha-carbonic anhydrase from Leptonychotes weddellii with a Ki value of 60,000 nM. Additionally, Sodium carbonate demonstrates bioactivity against human pathogens, showing inhibition of CA enzymes from organisms such as Helicobacter pylori, Sulfurihydrogenibium yellowstonense, Plasmodium falciparum, and Burkholderia pseudomallei. The compound also exhibits antifungal properties, inhibiting the growth of species like Fusarium verticillioides and Lasiodiplodia theobromae in vitro. Overall, these inhibitory effects, as evidenced by varying Ki values in the nanomolar range, suggest Sodium carbonate's potential utility in modulating CA-related physiological and pathological processes..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Sodium carbonate (Soda Ash) , is the disodium salt of carbonic acid with alkalinizing property.
Synonyms	Soda Ash, Disodium carbonate, Carbonic acid disodium salt

Chemical Properties

Molecular Weight	105.99
Formula	CNa₂O₃
Cas No.	497-19-8
Smiles	O=C([O-])[O-].[Na+].[Na+]
Relative Density.	2.53 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 20 mg/mL (188.7 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	9.4349 mL	47.1743 mL	94.3485 mL	471.7426 mL
5 mM	1.8870 mL	9.4349 mL	18.8697 mL	94.3485 mL
10 mM	0.9435 mL	4.7174 mL	9.4349 mL	47.1743 mL
20 mM	0.4717 mL	2.3587 mL	4.7174 mL	23.5871 mL
50 mM	0.1887 mL	0.9435 mL	1.8870 mL	9.4349 mL
100 mM	0.0943 mL	0.4717 mL	0.9435 mL	4.7174 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.