Ruxolitinib (INCB018424)
Referência orb180800-1g
Tamanho : 1g
Marca : Biorbyt
Catalog Number | orb180800 |
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Category | Small Molecules |
Description | Ruxolitinib is a potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5 nM, respectively and is relatively less selective for JAK3 (IC50 = 322 nM). |
CAS Number | [941678-49-5] |
MW | 306.37 |
SMILES | C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3 |
Formula | C17H18N6 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |