RPL3 Antibody - middle region
Referência OAAB09713
Tamanho : 400ul
Marca : Aviva Systems Biology
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RPL3 Antibody - middle region (OAAB09713)
| Datasheets/Manuals | Printable datasheet for RPL3 Antibody - middle region (OAAB09713) |
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| Publications | Altered Conformational Landscape upon Sensing Guanine Nucleotides in a Disease Mutant of Elongation Factor-like 1 (EFL1) GTPase |
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| Tested Species Reactivity | Human |
| Predicted Species Reactivity | Bovine|Human|Mouse|Porcine|Primate|Rabbit|Rat|Yeast |
| Product Format | Liquid PBS with 0.09% (W/V) sodium azide. |
| Clonality | Polyclonal |
| Isotype | Ig |
| Host | Rabbit |
| Application | IHC-P,WB |
| Additional Information | Cellular Location: Nucleus, nucleolus. Cytoplasm. |
| Reconstitution and Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | This RPL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-251 amino acids from the Central region of human RPL3. |
| Purification | This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Concentration | 0.5 mg/ml |
| Sample Type Confirmation | RPL3 is strongly supported by BioGPS gene expression data to be expressed in MDA-MB435 |
| Application Info | WB: 1:1000 IHC-P: 1:10~50 |
| Gene Symbol | RPL3 |
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| Alias Symbols | 60S ribosomal protein L3, ASC-1, F2, HIV-1 TAR RNA-binding protein B, J1, J1 protein, L3, L4, large ribosomal subunit protein uL3, Maintenance of killer protein 8, MAK8, ribosomal 60S subunit protein L3, ribosomal protein L3 homolog, RP1, TARBP-B, TCM1, Trichodermin resistance protein, YL1, YOR063W, YOR29-14. |
| NCBI Gene Id | 27367|282688|300079|6122|854229 |
| Protein Name | 60S ribosomal protein L3|60S ribosomal protein L3 isoform a [Homo sapiens] |
| Description of Target | Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL3 plays a role in coordinating processes of accommodating the aminoacyl-tRNA in the PTC.|The L3 protein is a component of the large subunit of cytoplasmic ribosomes. |
| Uniprot ID | P14126|P21531|P27659|P39023|P39872|Q29293|Q4R5Q0 |
| Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_000958.1 |
| Molecular Weight | 46109 |
