Resveratrol
Referência OOAU00072-100MG
Tamanho : 100mg
Marca : Aviva Systems Biology
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| Datasheets/Manuals | Printable datasheet for Resveratrol (OOAU00072) |
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| Product Format | Off white powder |
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| Additional Information | Background: A potent SIRT1 activator and a phytoestrogen with antitumor, antioxidant, antiplatelet, anti-inflammatory and antifungal effects. Inhibits cytochrome P450 1A1 (IC50 = 23 uM) and displays mixed agonist/antagonist actions at ERa and ERb estrogen receptors. Trans-Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. trans-Resveratrol is also a selective inhibitor of cyclooxygenase-1 (COX-1). It inhibits COX and peroxidase activities of COX-1 with ED50 values of 15 and 3.7 uM, respectively. There is essentially no inhibition of the COX-2 activity. Resveratrol also activates sirtuins and, extends lifespan in C. elegans. Converted into the anticancer agent piceatannol by cytochrome P450 1B1. |
| :: | Features: SIRT1 activator. Potent phenolic antioxidant. Selective inhibitor of cyclooxygenase-1 |
| :: | CAS Number: 501-36-0 |
| :: | Chemical Formula: C14H12O3 |
| Reconstitution and Storage | RT |
| Alias Symbols | 5-[(1E)-2-(4-hydroxyphenyl)ethenyl]-1,3-benzenediol |
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| Molecular Weight | 228.25 |