Interleukin 8 (IL-8, CXCL8, 310C, AMCF1, b-ENAP, Beta Thromboglobulin-like Protein, Emoctakin, Granulocyte Chemotactic Protein 1, GCP1, K60, LECT, LUCT, Lymphocyte-derived Neutrophil Activating Factor, LYNAP, MONAP, Monocyte Derived Neutrophil Activating Peptide, MDNCF, MDNCF alpha, Neutrophil Activating Factor, NAF, NAP1, Protein 310C, SCYB8, T cell Chemotactic Factor, TSG1) (Biotin)

CXCL8, also known as IL-8, is a chemoattractant that recruits neutrophils to sites of inflammation, activates neutrophil functions and promotes angiogenesis. CXCL8 production is rapidly induced by pro-inflammatory signals in many different cell types. The biological activites of CXCL8 are mediated by chemokine receptors CXCR1 and CXCR2. Feline CXCL8 is translated as a 101aa precursor protein with a 22aa signal peptide. It shares 61% and 76% aa sequence identity with human and canine CXCL8, respectively.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 0.5-2ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.