PTD2 TFA

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Referência NB-64-44345-25mg

Tamanho : 25mg

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Telefone : +1 850 650 7790

Marca : Neo Biotech

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Contactar o distribuidor local :

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PTD2 TFA

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Synonyms:

Catalog No. T83850 Copy Product Info

PTD2, derived from the histone 4 sequence, acts as a peptide inhibitor against Wolf-Hirschhorn syndrome candidate 1 (WHSC1; IC50 = 22 µM), a histone methyltransferase.

For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity

Description	PTD2, derived from the histone 4 sequence, acts as a peptide inhibitor against Wolf-Hirschhorn syndrome candidate 1 (WHSC1; IC50 = 22 µM), a histone methyltransferase.

Chemical Properties

Molecular Weight	597.80
Formula	C₂₇H₅₁N₉O₆.XCF₃COOH
Smiles	NC([C@@]([C@H](CC)C)(03)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](C(C)C)NC(CNC(C)=O)=O)=O)CCCC)=O)=O)=O.OC(C(F)(F)F)=O
Sequence	Ac-Gly-Val-Nle-Arg-Ile-NH₂
Sequence Short	GVXRI

Storage & Solubility Information

Storage

Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

PBS pH 7.2: 1 mg/mL (1.67 mM), Sonication is recommended.

DMSO: 10 mg/mL (16.73 mM), Sonication is recommended.

DMF: 2 mg/m, Sonication is recommended.

Solution Preparation Table

PBS pH 7.2/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6728 mL	8.3640 mL	16.7280 mL	83.6400 mL

DMSO

	1mg	5mg	10mg	50mg
5 mM	0.3346 mL	1.6728 mL	3.3456 mL	16.7280 mL
10 mM	0.1673 mL	0.8364 mL	1.6728 mL	8.3640 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Related Tags: PTD2 TFA chemical structure | PTD2 TFA formula | PTD2 TFA molecular weight