Polyclonal Antibody to Substance P (SP)

Referência PAA393Hu01-20ul

Tamanho : 20ul

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  • Product No.PAA393Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourcePolyclonal antibody preparation
  • HostRabbit
  • Potencyn/a
  • Ig Type IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen SPA393Hu01-Synthetic Substance P (SP)
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration500µg/mL
  • Organism Species MoreRattus norvegicus (Rat)
  • ApplicationsIHC
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • DownloadInstruction Manual
  • UOM 20µl100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against SP. It has been selected for its ability to recognize SP in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine Citations
Journal of Veterinary Internal Medicine A Potential Role for Substance P and Interleukin-6 in the Cerebrospinal Fluid of Cavalier King Charles Spaniels with Neuropathic Pain Pubmed: 23659719
Pharmacol Res Oral curcumin has anti-arthritic efficacy through somatostatin generation PubMed: 25836921
Applied Biological Chemistry Positive enhancement of Lactobacillus fermentum HY01 on intestinal movements of mice having constipation 10.1007/s13765-017-0327-3
CNS Neuroscience & Therapeutics  Direct activation of tachykinin receptors within baroreflex afferent pathway and neurocontrol of blood pressure regulation Pubmed:29900692
Journal of Veterinary Science Serum Levels of Neuropeptides in Cows with Left Abomasal Displacement Pubmed: 30562932
Respiratory Physiology & Neurobiology Effects of nanoparticles on Neuroinflammation in a Mouse Model of Asthma Pubmed: 31542455
Chinese Medicine Hejie Zhitong prescription promotes sleep and inhibits nociceptive transmission-associated neurotransmitter activity in a rodent migraine model Pubmed: 33014123
Medical Research Journal Changes of substance P, NGF and CGRP salivary levels among patients undergoing physical therapy
Int Urol Nephrol Evaluation of the causes affecting the development of pruritus in patients with peritoneal dialysis 34213714
J Chem Neuroanat Surfactant protein C is associated with perineuronal nets and shows age-dependent changes of brain content and hippocampal deposits in wildtype and 3xTg mice 34626771

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