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Dispatch Time: About 3 working days
- Product Name
- Phospho-Smad3(S423/S425) antibody
- Catalogue No.
- FNab10996
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- SMAD family member 3
- Alternative Names
- Mothers against decapentaplegic homolog 3 (MAD homolog 3 antibody, Mad3 antibody, Mothers against DPP homolog 3 antibody, hMAD-3)|JV15-2|SMAD family member 3 (SMAD 3 antibody, Smad3 antibody, hSMAD3)|SMAD3|MADH3 antibody
- UniProt ID
- P84022
- Observed MW
- 55 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:1000; IHC: 1:50 - 1:200
Validated Images
C2C12 cells treated by TGF-β (10 ng/ml) at 37℃ for 30 minutes were subjected to SDS PAGE followed by western blot with FNab10996 at dilution of 1:600 - Background
- The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.